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Pathology Haematology ec156b81

Isolated deletion of which chromosome causes Myelodysplastic syndrome ?

A
2q
B
5q
C
8q
D
11q
High-Yield Explanation
Both primary and t- MDS are associated with recurrent chromosomal abnormalities including monosomies 5 and 7, deletions of 5q, 7q, and 20q and trisomy 8. Ref : Robbins and Cotran Pathologic basis of disease.South Asia Edition volume 1.page no. 614,615

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