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Biochemistry Vitamins and Minerals ec0304db

A girl licks paint that is peeled of from the toys, develop acute abdominal pain, tingling sensation of hands and legs and weakness. Which enzyme is inhibited in this child?

A
ALA synthase
B
Heme oxygenase
C
Coproporphyrinogen oxidase
D
ALA dehydratase
High-Yield Explanation
Ans. D. ALA dehydratasePaints contain lead hence it is most probably lead poisoning. Biochemical effects of lead poisoning are:Inhibition of ALA dehydratase >> Ferro chelataseIncreased ALA excretion in urine. Increased ALA synthase activity.

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