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Biochemistry General eb63c815

False statements are

A
Multiple origins of replication are possible for bacteria
B
DNA replication proceeds in one direction
C
Lagging strand stick by RNA primase
D
All of these
High-Yield Explanation
In leading strands, DNA is synthesized continuously by DNA polymerase III. Bacteria have only single origins of replication as their DNA is circular. In lagging strand, Okazaki fragments are sticked by ligase, not by primase. Option 'c' is a tricky one. DNA replication proceeds in 5' → 3' on both strand. But as both parent strands are antiparallel, synthesis on leading strand is toward the replication fork, while synthesis on lagging strand is away from replication form (i.e. in opposite direction).

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