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Anaesthesia General eb5629af

Which of the following are features of pulmonary oxygen toxicity?

A
Increased capillary endothelial permeability
B
Decreased mucociliary transpo in airways
C
Inhibition of phagocytosis function of alveolar macrophages
D
All the above
High-Yield Explanation
Ans. is 'd' i.e., All the above Prolonged inhalation of high concentration of 0, is known to damage the lungs. Pulmonary toxicity of 0, is related to the oxygen tension in alveoli. The pulmonary oxygen toxicity has the following features Increased capillary endothelial permeability causing accumulation of fluid in the interstitial space. Depression of mucociliary transpo function of airway Inhibition of phagocytosis of alveolar macrophages Changes in the surfactant activity and its production.

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