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Biochemistry General eae80b34

Which among the following is the major hemoglobin found in fetus?

A
Hb Gower-1
B
Hb F
C
Hb Gower-2
D
Hb Poland
High-Yield Explanation
Hb F (22) is the major hemoglobin of fetal life. After 34 to 36 weeks' gestation the percentage of Hb A rises, whereas that of Hb F decreases. Hb Gower-1 (22) is the major hemoglobin in embryos younger than 5 weeks' gestation. Hb Gower-2 (22) has been found in embryos with a gestational age as young as 4 weeks and is absent in embryos older than 13 weeks. Hb Poland (22) is found in young embryos. Ref: Palis J., Segel G.B. (2010). Chapter 6. Hematology of the Fetus and Newborn. In J.T. Prchal, K. Kaushansky, M.A. Lichtman, T.J. Kipps, U. Seligsohn (Eds), Williams Hematology, 8e.

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