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Pathology General ea7e2725

Which of the following is false about Wilm's tumor:September 2010

A
Presents before the age of 5 years
B
Mostly presents as abdominal mass
C
Spreads mostly by lymphatics
D
Responds well to treatment
High-Yield Explanation
Ans. C: Spreads mostly by lymphaticsWilms' tumor or nephroblastoma is cancer of the kidneys that typically occurs in children, rarely in adults. The majority (75%) occur in otherwise normal children (1-6 years); a minority (25%) is associated with other developmental abnormalities.It is highly responsive to treatment, with about 90% of patients surviving at least five years.Most nephroblastomas are unilateral, being bilateral in less than 5% of cases.They tend to be encapsulated and vascularized tumors that do not cross the midline of the abdomen.In cases of metastasis it is usually hematogenous and to the lung.

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