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Pediatrics Gastrointestinal tract ea655f25

False about kernicterus is _______

A
No long term effect
B
Occurs with bilirubin more than 25 mg %
C
Deposition in basal ganglion
D
Opisthotonus
High-Yield Explanation
When blood level of bilirubin is more than 20 mg/dl the capacity of albumin to bind bilirubin is exceeded.in young children before the age of i year, the blood brain barrier is not fully developed and therefore free bilirubin enters the brain .It is deposited in basal ganglia,leading to mental retardation,fits,encephalitis and spasticity. Ref : TEXTBOOK OF BIOCHEMISTRY,D.M.VASUDEVAN,PG NO:252,6th edition

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