Chloroma is due to –

Clinical features of AML The clinical findings in AML are similar to those in ALL i.e., suppression of normal hematopoisis in the marrow that results in - Anemia → Fatigue, pallor Neutropenia → Infection, Fever Thrombocytopenia → Spontaneous mucosal and cutaneous bleeding. This is the most striking clinical feature. Others Tumor cells in acute promyelocytic leukemia (M3) release procoagulant and fibrinolytic factors that cause Disseminated hatravascular coagulation IC). Monocytic differentiation type (M4 and M3) may present with infiltration of skin (leukemia cutis) and gingival hypertrophy. Chloromas (granulocytic sarcomas or myeloblastomas) are localize masses composed of myeloblasts in the absence of marrow or peripheral blood involvement. Lymphodenopathy, Hepatosplenomegaly, CNS involvement and testicular involvement are less common than ALL.