Which of the following is not a major criteria for diagnosis of multiple myeloma?
High-Yield Explanation
"Lytic bone lesions" is not a major criteria for the diagnosis of multiple myeloma. It is a minor criteria for the diagnosis of multiple myeloma. So "Lytic bone lesions" is the single best answer of choice. Ref: The Washingtom Manual of Surgical Pathology: Depament of Pathology By Peter A Humphrey, Loius P.Dehner, Ohn D. Pfeifer, Page 565.