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Pharmacology General e9962660

Aldosterone antagonists are NOT useful in the treatment of-

A
Hypeension
B
Congestive hea failure
C
Gynaccomastia
D
All
High-Yield Explanation
Ans. is 'c' i.e., Gynaecomastia Spironolactone is a weak diuretic and can be used only in combinations with other more efficient diuretics? 1) Edema o It is more useful in cirrhotic and neph retie edema because in these conditions aldosterone level is high. o Spironolactone is the drug of choice for cirrhotic edema. 2) To counteract K+ loss due to thiazide and loop diuretics - 3) Hypeension 4) CHF

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