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Pharmacology Anti-Cancer e98c3402

Cardiotoxicity is the side effect of

A
Bleomycin
B
Topotecan
C
Rubidomycin
D
Procarbazine
High-Yield Explanation
Ans. is 'c' i.e., Rubidomycin Anthracycline induced cardiotoxicity* Rubidomycin and doxorubicin are the anthracycline anti - tumor antibiotics* They have cardiotoxicity as a adverse effect.* This can manifest either acutely with ECG changes, arrhythmias and hypotension, which are reversible, or be delayed like CHF.* CHF is due to cardiomyopathy and may be fatal.* To prevent the chances of anthracycline induced cardiomyopathy, antioxidants like dexrazone can be used.

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