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Pharmacology Chemotherapy e962330a

Which of the following drugs is Topoisomerase 1 inhibits

A
Doxorubicin
B
Irinotecan
C
Etopside
D
Vincristine
High-Yield Explanation
Refer KDT 6/e p 825, Camptothecin derivatives like topotecan and irinotecan act by inhibiting Topoisomerase -1whereras epipodophylotoxins and anthracycline act by inhibiting Topoisomerase -2

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