A 60-year-old woman has a history of being treated for endometrial cancer with surgery and radiation 5 years ago. She now presents with a large necrotic tumor that follows the course of the sciatic nerve. Which of the following is the most likely diagnosis
High-Yield Explanation
The development of a necrotic tumor involving a peripheral nerve in an area that was irradiated previously is characteristic of a malignant peripheral nerve sheath tumor. Ref:- Harsha Mohan textbook of Pathology