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Pathology General e8990fe2

Ram Devi presented with generalized edema sweating and flushing tachycardia and fever after bee sting. This is -

A
T cell mediated cytotoxicity
B
IgE mediated reaction
C
IgG mediated reaction
D
IgA mediated hypersensitivity reaction
High-Yield Explanation
Ans. is 'b' i.e., IgE mediated reaction o The symptoms of the patient are d/t hypersensitivity type I reaction Type I is mediated by IgE and it flairs up within minutes. o There are typical features of anaphylaxis (systemic Type I hypersensitivity). Clinical manifestations of anaphylaxis o Flushing and tachycardia are usually the first and are invariant symptoms of anaphylaxis. o Uicaria (pruritis) o Angiodema o Respiratory distress and wheezing due to bronchoconstriction. o Confusion and alteration of mental status can occur.

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