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Pharmacology General e88e2bd0

All of the following are characteristic features of treatment of iron deficiency anemia with oral iron supplements, except :

A
If 200–300 mg elemental iron is consumed, about 50 mg is absorbed
B
The proportion of iron absorbed reduces as hemoglobin improves
C
The reticulocyte count should begin to increase in two weeks and peak in 4 weeks. This suggests good response to treatment
D
The treatment should be discontinued immediately once hemoglobin normalizes to prevent side effects of iron.
High-Yield Explanation
A normal individual without iron deficiency absorbs 5-10% of iron, or about 0.5-1 mg daily. Iron absorption in­creases in response to low iron stores or increased iron requirements In an iron deficient individual, about 50-100 mg of iron can be incorporated into hemoglobin daily, and about 25% of oral iron given as ferrous salt can be absorbed. Therefore, 200-400 mg of elemental iron should be given daily to correct iron deficiency most rapidly. The reticulocyte count should begin to increase in two weeks and peak in 4 weeks. This suggests a good response to treatment Treatment with oral iron should be continued for 3-6 months. This will correct the anemia and replenish iron stores.

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