Full 2L QBank
Pathology General pathology e86b0418

Which type of Amyloidosis is caused by mutation of the transthyretin protein ?-

A
Familial Mediterranean fever
B
Familial amyloidotic polyneuropathy
C
Dialysis associated amyloidosis
D
Prion protein associated amyloidosis
High-Yield Explanation
In contrast with familial Mediterranean fever, a group of autosomal dominant familial disorders is characterized by deposition of amyloid predominantly in the peripheral and autonomic nerves. These familial amyloidotic polyneuropathies have been described in kindreds in different pas of the world--for example, in Pougal, Japan, Sweden, and the United States. As mentioned previously, the fibrils in these familial polyneuropathies are made up of mutant forms of transthyretin (ATTRs). Robbins 9 th edition page no. 156

Related Pathology MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now