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Surgery G.I.T e7c3b25e

Vaccine for post splenectomy infection is given against all except :

A
Streptococcus pneumonia
B
Haemophilia influenza
C
Neisseria meningitides
D
E.coli
High-Yield Explanation
Splenectomy : Most serious sequela is overwhelming postsplenectomy infection (OPSI), with meningitis, pneumonia, or bacteraemia OPSI is typically caused by polysaccharide-encapsulated organisms, such as Streptococcus pneumoniae, Neisseria meningitidis & Hemophilus influenzae When elective splenectomy us planned, vaccination against encapsulated bacteria should be given atleast 2 weeks before surgery If spleen is removed in emergency, vaccination should be given as soon as possible Vaccines should be given for Streptococcus pneumoniae, Hemophilus influenza type B & Meningococcus In addition to above given 3 vaccines, annual influenza immunization is also advised as influenza has been implicated as a risk factor for secondary bacterial infections Booster injections of pneumococcal vaccine should be given every 5-6 years Harrison says "Routine Chemoprophylaxis with oral penicillin can result in the emergence of drug-resistant strains and is not recommended" Ref: Sabiston 20th edition Pgno : 1564

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