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Pathology miscellaneous e7676b9b

Marker of glomus tumor -

A
CD-57
B
Cytokeratin
C
S-100
D
CD-34
High-Yield Explanation
Additional studies using immunohistochemical techniques revealed that malignant glomus tumors are characterized by the presence of MIB-1, p53, Bcl-2, and CD34. Up to 4% of the tumors are functional and produce clinically significant levels of catecholamines, norepinephrine, or dopamine with symptoms mimicking a pheochromocytoma. Pheochromocytoma, parathyroid adenoma, and thyroid carcinoma have been repoed in association with glomus jugulare tumors. Ref: Medscape

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