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Social & Preventive Medicine General e7605d32

ELISA is performed on a population with low prevalence. What would be the result of performing double screening ELISA tests -

A
Increased sensitivity and positive predictiv value
B
Increased sensitivity and negative predictive value
C
Increased specificity and positive predictive value
D
Increased specificity and negative predictive value
High-Yield Explanation
The specificity of ELISA can be increased by carrying out ELISA in a row (series) using different HIV markers. When screening test is used in a series mode : - ↑ Specificity ↑ PPV ↓ Sensitivity

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