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Pathology General e75f5896

True about celiac disease -

A
Villous atrophy
B
Crypt hyperplasia
C
Infiltration of lymphocytes
D
All
High-Yield Explanation
Ans. is 'a' i.e., Villous atrophy; 'b' Crypt hyperplasia; 'c' i.e., Infiltration of lymphocyteso Characteristic histopathological features in celiac disease are:(t) Intraepithelial lymphocytosis (Increased numbers of intraepithelial CD8 + T lymphocytes).(ii) Crypt hyperplasia(iii) Villous atrophyCryptitis refers to inflammation of an intestinal crypt. It is not a feature of celiac disease. It is seen in Inflammatory bowel disease (CD, UC), diveicular disease, radiation colitis and infectious colitis.

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