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Gynaecology & Obstetrics General e7339d15

A female developed ovarian hyperstimulation syndrome during the treatment of infeility. What is the MOST common cause of ovarian hyperstimulation?

A
FSH/LH therapy
B
GnRH drugs
C
Clomiphene
D
Danazol
High-Yield Explanation
Ovarian hyperstimulation syndrome (OHSS): It is a clinical symptom complex associated with ovarian enlargement resulting from exogenous gonadotropin therapy. Symptoms may include abdominal pain and distension, ascitis, gastrointestinal problems, respiratory compromise, oliguria, hemoconcentration, and thromboembolism. These symptoms may develop during ovulation induction or in early pregnancies that were conceived through exogenous ovarian stimulation. Ref: Hoffman B.L., Schorge J.O., Schaffer J.I., Halvorson L.M., Bradshaw K.D., Cunningham F.G., Calver L.E. (2012). Chapter 20. Treatment of the Infeile Couple. In B.L. Hoffman, J.O. Schorge, J.I. Schaffer, L.M. Halvorson, K.D. Bradshaw, F.G. Cunningham, L.E. Calver (Eds), Williams Gynecology, 2e.

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