Type II hypersensitivity is mediated by -

Antibody mediated Type I reactions (immediate hypersensitivity) → Involve immunoglobulin ‘E’(Ig E) mediated release of Histamin and other mediators from mast cells and basophils. Type II reactions (Antibody mediated) → Involve immunoglobulin Gor Immunoglobulin Mbound to cell surfac antigen, with subsequent complement fixation. Type III reactions (Immune complex mediated) → involve circulating antigen-antibody complexes that deposit ii postcapillary venules, with subsequent complement fixation. Type IV reactions (delayed hvpersensititv. cell mediated) → Mediated by Tcells.