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Pathology Endocrinology e6f2c9b3

Which of the following mechanisms is not responsible for complications in DM

A
Non enzymatic glycosylation
B
Protein Kinase C activation
C
Disturbance in polyol pathway
D
Chronic inflammation
High-Yield Explanation
The things responsible for chronic complications of DM are 1)Formation of Advanced glucation end products 2) Activation of Protein Kinase C 3)Oxidative stress and disturbance in Polyol pathways . Possible complications include: Cardiovascular disease. ... Nerve damage (neuropathy). ... Kidney damage (nephropathy). ... Eye damage (retinopathy). ... Foot damage. ... Skin conditions. ... Hearing impairment. ... Alzheimer's disease Ref: Robbins and cotrans 9e Pg 1116

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