Albumin is impoant factor in maintaining osmotic pressure, has:

A i.e. Low molecular weight and high blood concentration Osmotic pressure is determined by the number of paicles in solution and not by the mass of the paicle, that means 1 gm of a heavy molecular weight protein will contain a lesser no. of paicles than 1 gm of a light molecular weight protein, & conse uentiv will have a lesser osmotic pressure Plasma protein MW Concentration Contribution to plasma osmolality Albumin 69,000 3.5-5 gm% 80% Globulin 1,40,000 2.0 gm% 20% Fibrinogen 4,00,000 0.3 gm% 0% Of the there major types of plasma protein, albumin with minimum molecular weight contributes. max to plasma oncotic pressure.