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Pathology Kidney e6c230b5

An 8-year-old boy presents with headaches, dizziness, and malaise. He was seen for a severe sore throat 2 weeks ago. Physical examination reveals facial edema. The blood pressure is 180/110 mm Hg. A 24-hour urine collection demonstrates oliguria, and urinalysis shows hematuria. What finding on microscopic urinalysis indicates that hematuria in the patient is caused by a renal process, rather than bleeding from another site in the urinary tract?

A
Blood clots
B
Hemoglobin crystals
C
Phagocytosed hemoglobin
D
Red blood cell casts
High-Yield Explanation
Injury to the glomerular capillaries results in spillage of protein and blood cells into the urine. Hematuria is also seen in patients with bleeding from the lower urinary tract. However, RBC casts in the urine sediment originate from erythrocytes compacted during passage through the renal tubules and denote a renal origin of hematuria.Diagnosis: Postinfectious glomerulonephritis, nephritic syndrome

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