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Pathology Kidney disorders e6b07b5c

All are true about nephronophthisis except:

A
Interstitial fibrosis
B
Coical tubular hyperophy
C
Cysts in the medulla
D
20% cases are non-familial
High-Yield Explanation
2 types of cystic disease affecting the renal medulla are : 1. Medullary sponge kidney Relatively common Usually innocuous condition Associated with nephrolithiasis 2.Nephronophthisis- Medullary cystic disease complex Associated with renal dysfunction. Cause of chronic kidney disease that usually begins in childhood. Coical tubulointerstitial damage and not hyperophy occurs in nephronophthisis.

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