What is the most common cause of pyogenic liver abscess
High-Yield Explanation
Routes of infection Biliary tract (Most Common) - CBD stones leading to cholangitis, Hilar carcinoma in Western countries, CBD strictures Poal vein (2nd most common) Hepatic aery - Hematogenous spread, usually monimicrobial, Staphylococcus or streptococcus Direct extension- from subdiapragmatic abscess, from suppurative cholecystitis, from empyema in chest, from perinephric abscess Penetrating or blunt trauma Cryptogenic Ref: Sabiston 20th edition