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Pharmacology Targeted Anticancer Drugs and Immunosuppressants e61b84eb

Which of the following drugs used in the therapy of metastatic melanoma is a MEK inhibitor?

A
Vemurafenib
B
Ipilimumab
C
Dabrafenib
D
Trametinib
High-Yield Explanation
MEK INHIBITORS: Trametinib, Binimetinib, Cobimetinib Reversible inhibitor of mitogen-activated extracellular signal regulated kinase (MEK). Used in the treatment of MALIGNANT MELANOMA Dabrafenib and vemurafenib are BRAF inhibitors used in MALIGNANT MELANOMA. Ipilimumab is a monoclonal antibody against CTLA-4. It is also approved for treatment of malignant melanoma.

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