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Pharmacology Chemotherapy: General Principles e5644567

Figure shows the mechanism of action of:

A
Vinblastine
B
Cisplatin
C
Imatinib
D
Trastuzumab
High-Yield Explanation
Ans. (A) VinblastineThe mechanism shows the inhibition of polymerization of tubulin means the drug inhibit the spindle formation. This mechanism is shown by vinca alkaloids like vincristine and vinblastine.Mechanism on spindleDrugsInhibit polymerization of tubulinVincristine, VinblastineInhibit depolymerization of tubulinPaclitaxel, Docetaxel

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