Pro-inflammatory Cytokines include all of the following except -

Cytokines are involved in the immunological reaction, but some cytokines may also take part in inflammation. o They may be: - 1. Proinflammatory cytokines Involved in the amplification of inflammation and tissue destruction. IL-1 & TNF-a are the two most important proinflammatory cytokines. IL-6 may also act as a proinflammatory cytokine. Other proinflammatory cytokines are IL-2, IL-4, IL-5, IL-6, IL-8, IL-I1, IL-12, IL-15, IL-21, IL-23, IFN-gamma and granulocyte-macrophage colony-stimulating factor (GM-CSF). ( Source Fundamental immunology by William E. Paul). 2 Anti inflammatory cytokines Reduce inflammation and produce healing, Example are IL-4, IL-13, IL-1, IL-10