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Pathology General pathology e49b493d

Kilnefelter no of chromosomes

A
47
B
46
C
45
D
44
High-Yield Explanation
Klinefelter syndrome is best defined as male hypogonadism that develops when there are at least two X chromosomes and one or more Y chromosomes. Most affected patients have a 47,XXY karyotype. This karyotype results from nondisjunction of sex chromosomes during meiosis. The extra X chromosome may be of either maternal or paternal origin. (Robbins Basic Pathology, 9 th edition. page : 239)

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