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Biochemistry Metabolism of nucleic acids e471fb45

Protein that initiates synthesis of RNA primers

A
SSBs
B
DNA Ligase
C
DNA Primase
D
Topoisomerases
High-Yield Explanation
Classes of Proteins Involved in Replication Protein Function DNA polymerases Deoxynucleotide polymerization Helicases ATP -driven processive unwinding of DNA Topoisomerases Relieve torsional strain that results from helicase-induced unwinding DNA primase Initiates synthesis of RNA primers Single-strand binding proteins (SSBs) Prevent premature reannealing of dsDNA DNA ligase Seals the single strand nick between the nascent chain and Okazaki fragments on lagging strand Harper30e pg: 378

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