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Physiology General e4130c5f

True regarding HbA2 is/are?

A
It has more capacity to carry oxygen
B
Concentration is more than HbA
C
Level is increased in Thalasemia
D
Consists of 2 alpha and 2 beta chains
High-Yield Explanation
Ans. is'c'i.e., Level is increased in ThalassemiaRef: Ganong 23d/e p. 523-525 https: / /www. aafp.org/ alp / 2009 /08 1 5 /p3 39.html"The hemoglobin electrophoresis with beta thalassemia trait usually has reduced or absent HbA, elevated levels of HbA2. and increased HbF.However, a normal concentration of HbA2 does not rule out beta thalassemia trait. especially if there was coexistent iron deficiency, which can lower HbA2 levels into the normal range.""Hemoglobin A2 may be increased in beta thalassemia or in people who are heterozygous for the beta thalassemia gene.

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