Hypervitaminosis of which of the following wil cause bony abnormalities: (A) Vit. A (B) Vit. D (C) Vit C (D) Vit. E (E) Vit. K

"Vit D excess increase intestinal calcium absorption & if severe ,also increase bone resorption 7 " - H17th/2387 “Vit. A intoxication cause hypercalcemia & presumed to increase bone resorption Q - H17th/2387 Metabolic Bone Disease Q The common metabolic bone disease is associated in varying degree with depletion of bone tissue or bone mineral & [in some cases) with systemic features of altered mineral metabolism The most common condition fall into three groups: 1. Osteoporosis-in which the quantity of bone mass' 3 is abnormally low 2. Osteomalacia- in which the osseous connective tissue [osteoid) is present but insufficiently mineralised' 3 3. Osteitis fibrosa- in which PTH overproduction leads to bone resorption 13 & replacement by fibrous tissue