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Social & Preventive Medicine General e34d867e

Due to an effective prevention program, the prevalence of an infectious disease in a community has been reduced by 90%. A physician continues to use the same diagnostic test for the disease that she has always used. How have the test's characteristics changed ?

A
Its sensitivity has increased
B
Its positive predictive value has increased
C
Its negative predictive value has increased
D
The test's characteristics have not changed
High-Yield Explanation
PPV and NPV of a screening test depends on: Sensitivity Specificity Prevalence of disease in the population In this question, since a physician continues to use the same diagnostic test for the disease that she has always used, sensitivity and specificity of the test will remain same But predictive value of a test (PPV and NPV) depends on prevalence of a disease in a population PPV is directly proportional to prevalence of disease in the population PPV α Prevalence of disease As the prevalence of a disease increases in a population, PPV increases for the screening test NPV is inversely proportional to Prevalence of disease in a population NPV α 1/ Prevalence of disease As the prevalence of a disease increases in a population, NPV decreases for the screening test. Therefore, since the prevalence of an infectious disease in a community has been reduced by 90%, its PPV will reduce and its NPV will increase.

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