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Pharmacology General e34b7e97

Exocytic release of ACH is blocked by ?

A
Hemicholium
B
Botulinum
C
Alpha bungarotoxind
D
Vesamicol
High-Yield Explanation
Ans. is 'b' i.e., Botulinum ACETYLCHOLINE SYNTHESIS AND RELEASE Choline is actively taken up by the axonal membrane by Na+; choline cotranspoer. (Rate limiting step). This step is blocked by Hemicholinium. Choline is acetylated with the help of ATP and coenzyme 'A' by the enzyme choline acetyl transferase present in the axoplasm.

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