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Pathology General e33efaeb

All are TRUE about myxomas in hea, EXCEPT:

A
Most common primary tumor of the hea
B
Associated with clonal abnormalities of chromosomes 12 and 17
C
90% are located in the atria
D
Never occur on hea valves
High-Yield Explanation
Myxomas are the most common primary tumor of the hea in adults. They are benign neoplasms often associated with clonal abnormalities of chromosomes 12 and 17 that are thought to arise from primitive multipotent mesenchymal cells. Although they may arise in any of the four chambers or, rarely, on the hea valves, about 90% are located in the atria (atrial myxomas), with a left-to-right ratio of approximately 4 : 1. Ref: Robbins 8th edition Chapter 12.

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