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Pathology General e333e8d2

Which of the following is not true regarding apoptosis?

A
Step ladder pattern on agarose gel electrophoresis
B
Apoptosis is energy independent process.
C
Annexin V is a marker of apoptosis
D
Caspases are endonucleases
High-Yield Explanation
Caspases are cysteinyl aspartate proteinases. They are cysteine proteases that cleave their substrates following an aspartate residue. They will activate endonucleases leading to chromatin clumping.

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