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Microbiology General e2f79a74

True about Cryptococcus neoformans are all except: September 2005

A
Possess a prominent polysaccharide capsule
B
Abundant in pigeon droppings
C
Dimorphic fungi
D
Causes meningitis in the immunocompromised
High-Yield Explanation
Ans. C: Dimorphic fungi Cryptococcus is yeast/unicellular fungi. C neoformans is distributed worldwide. C neoformans, which is recovered from aged pigeon feces, bird nests, and guano, is invariably serotype A or D. Although serotypes A and D exist in high concentrations in the pigeon feces, the fungus does not infect the birds. In moist or desiccated pigeon excreta, C neoformans may remain ble for 2 years or longer. In saprobic environments, C neoformans grows unencapsulated; however, unencapsulated strains regain their virulence following reacquisition of their polysaccharide capsule. Cryptococcal meningitis is the most serious type of infection and can resemble tuberculous or other chronic type of meningitis. It is often seen in AIDS.

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