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Dental Bacterial infections e2efe119

All are true about propionibacterium acne except

A
Normal flora of skin
B
Gram negative
C
Can be found in GIT
D
Causes acne vulgaris
High-Yield Explanation
Propionibacterium acnes (P. acnes) * Gram +ve anaerobic rod, resident flora in follicle but acne patients with higher concentration * Naturally produces porphyrins (coproporphyrin III), which is the target of light-based acne therapy * Secretes lipases which cleave lipids in sebum into pro-inflammatory free fatty acids (FFAs), which are both comedogenic and chemotactic * Binds/activate toll-like receptor 2 (TLR2) * Causes Acne vulgaris. Ref:- Sima Jain; pg num:- 96

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