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Pharmacology Anti-HIV Drugs e2e0a964

The following are true about enfuviide except:

A
Administered by s.c route
B
Effective on HIV 1 and HIV 2 strains
C
Binds to HIV gp41
D
No cross resistance with other anti-retroviral drugs
High-Yield Explanation
Enfuviide It is an Entry (fusion) inhibitor. MOA: By binding to HIV-1 gp41 Active on HIV 1& not active against HIV-2. Cross resistance not seen with other classes of ARV drugs. Given s.c. twice daily. Used as add on drug for failed regimens. Adverse effects: Pain at injection site and it cause local nodules or cysts.

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