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Pharmacology All India exam e2c45706

Which of the following is not true about synol sarcoma? NOT RELATED -OHO

A
It does not arise from synovium
B
It occurs more common at extraaicular sites
C
It is seen at >50 yrs of age
D
Knee and foot are common sites involved
High-Yield Explanation
SYNOL SARCOMAa. Unrelated to the synoviumb. Histologic resemblance of synol cellsi. 2 types: monophasic, biphasicc. Fusion of genes between chromosome 18 and X chromosome - t(X,18)d. Age distribution: average age 35e. Presentation: Pain associated with deep-seated massf. The histologic hallmark of synol sarcoma is the biphasic morphology of tumor cellsg. t (x, 18) is characteristic of synol sarcoma.h. 4th most common soft tissue sarcomai. Location: Most commonly located around the kneej. Usually occurs within 7 cm of joint, but usually is not intra-aicular (only 10%intraaicular)k. Treatment: Wide resection with chemotherapy, especially with poorly differentiated lesions.l. Sensitive to Ifosfamide regimes

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