A married middle aged female gives history of repeated aboions for the past 5 years. The prenatal karyogram of the conceptus is given below: This karyogram suggests the following:

Karyogram shows 3 chromosomes at 21 instead of a pair. It is called Trisomy 21. Trisomy 21 Synonymous with Down's syndrome Most common of the chromosomal disorders. Major cause of mental retardation. -Other trisomies Edward syndrome (Trisomy 18) Patau syndrome (Trisomy 13) Turners syndrome (45 X0)