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Pharmacology General e2391994

A patient who was given primaquine develops dark coloured urine one day after administration of the drug. The likely diagnosis is -

A
Glucose-6-phosphate dehydrogenase deficiency
B
Glucose-6-phosphate deficiency
C
Galactose-6-phosphate dehydrogenase deficiency
D
Galactose-6-phosphataase deficiency
High-Yield Explanation
Ans. is 'a' i.e., Glucose-6-phosphate dehydrogenase deficiency o Development of dark coloured urine within one day of administration of primaquine suggests the possibility of intravascular hemolysis and hemoglobinuria. Primaquine can cause hemolysis in patients with G6PD deficiency.

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