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Pharmacology Kidney e1d65e4e

Which diuretic be considered appropriate for combining with ACE inhibitors?

A
Spironolactone
B
Eplerenone
C
Hydrochlorothiazide
D
Amiloride
High-Yield Explanation
Thiazides, loop diuretics produce hypokalemia which can be compensated with hyperkalemia produced by ACE inhibitors Potassium-sparing diuretics like spironolactone, eplerenone, amiloride - produce hyperkalemia- so not to be used with ACE inhibitors ( Essentials of medical pharmacology, K.D Tripathi, 6 th edition, page 568 )

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