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Pharmacology Anaesthesia e1b10c50

A patient receives a toxic dose of lignocaine i.v., the patient is likely to exhibit?

A
Excessive salivation
B
Mydriasis and diarrhea
C
Respiratory paralysis
D
Seizures and coma
High-Yield Explanation
* If LA reaches the blood stream, most prominent adverse effects are related to CNS and CVS. * In CNS :-stimulation (convulsions) followed by depression (coma) is seen. - Initial stimulation is due to inhibition of the inhibitory neurons.

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