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Psychiatry General e152cc89

Which of the following is a drug of choice for treatment of Obsessive Compulsive Disorder (OCD) in adults?

A
Imipramine
B
Fluoxetine
C
Chlopromazine
D
Benzodiazepine
High-Yield Explanation
The selective serotonin reuptake inhibitors (SSRIs) are now considered to be first-line drug treatments in the management of obsessive compulsive disorder. Fluoxetine is the drug of choice. The doses are usually higher than for anti-depressant action. Clomipramine is still considered as a good option when fluoxetine does not work. Clomipramine has the most specific seratoninergic effects among the Tricyclic Antidepressants (TCAs). Ref: Kaplan & Sadock's Synopsis of Psychiatry 9 Edition, Page 622-23, 209; Harrison's Principles of Internal Medicine 16th Edition, Page 2552; A Sho Textbook of Psychiatry by Neeraj Ahuja, 8th Edition, Page 100

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