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Pathology Endocrinology e13d4d48

Which of the following is not true about medullary carcinoma of thyroid ?

A
Origin is from 'C' cells of thyroid
B
Component of MEN- 1
C
Multicentric in origin
D
Amyloid deposition
High-Yield Explanation
Medullary carcinoma of thyroid is a neuroendocrine neoplasm which is multicentric and derived from C cells of thyroid. It is characterised by acellular amyloid deposits derived from calcitonin in stroma of the cells. It is a component of MEN 2A or MEN 2B and not MEN 1. Ref: Robbins and cotrans 9e Pg 1099 Ref IMG

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