Black widow spider toxin is known to cause

Excess release of Acetylcholine Black widow spider toxin Induces massive release and depletion of acetylcholine Decrease release of Acetylcholine Botulinum toxin Inhibits synthesis of Acetylcholine Hemicholinium (HC3) blocks choline uptake (the rate limiting step in Achsynthesis) and depletes Ach Active transpo of ACh into synaptic vesicle Inhibited by vesamicol