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Pharmacology C.N.S e0f57d04

Vigabatrin acts through -

A
decreasing GABA uptake at synaptic cleft
B
Increasing GABA uptake at synaptic cleft
C
GABA transaminase inhibitor
D
GABA transacetylase inhibitor
High-Yield Explanation
Ans. is 'c' i.e., GABA transaminase inhibitor Vigabatrin (g vinyl GABA)* It is a newer anti - convulsant which is an inhibitor of enzyme GABA transaminase; it thus increases GABA concentration at synapse.* It is mainly used in patients with refractory epilepsy visual field defects and behavioural changes restricts its use.

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